Frank Beier Selected Research

Chondrocalcinosis 2

6/2009	The CPPDD-associated ANKH M48T mutation interrupts the interaction of ANKH with the sodium/phosphate cotransporter PiT-1.
1/2008	The ANKH ΔE490Mutation in Calcium Pyrophosphate Dihydrate Crystal Deposition Disease (CPPDD) affects tissue non-specific Alkaline Phosphatase (TNAP) activities.

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Frank Beier Research Topics

Disease

27	Osteoarthritis 01/2021 - 01/2007
8	Hypertrophy 05/2012 - 06/2005
5	Neoplasms (Cancer) 02/2017 - 04/2004
4	Inflammation (Inflammations) 01/2022 - 04/2013
4	Colorectal Neoplasms (Colorectal Cancer) 02/2017 - 03/2015
4	Joint Diseases (Joint Disease) 08/2015 - 01/2009
3	Pain (Aches) 01/2021 - 02/2012
3	Knee Osteoarthritis 07/2020 - 11/2007
3	Squamous Cell Carcinoma of Head and Neck 01/2017 - 05/2013
2	Body Weight (Weight, Body) 01/2022 - 05/2012
2	Obesity 11/2021 - 01/2021
2	Necrosis 07/2020 - 08/2014
2	Disease Progression 01/2016 - 10/2015
2	Hypoxia (Hypoxemia) 01/2014 - 04/2013
2	ATR-X syndrome 12/2013 - 01/2013
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 09/2011 - 11/2010
2	Ankylosis 06/2009 - 01/2008
2	Chondrocalcinosis 2 06/2009 - 01/2008
2	Chondrosarcoma 04/2004 - 09/2002
1	Hyperalgesia 01/2022
1	Back Pain (Backache) 01/2021
1	Sclerosis 01/2021
1	Synovitis 01/2021
1	Arthralgia (Joint Pain) 01/2021
1	Rheumatoid Arthritis 01/2020
1	Arthritis (Polyarthritis) 01/2020
1	type 2 alpha 1 Collagenopathy 12/2018
1	Premature Aging 06/2018
1	Mental Disorders (Mental Disorder) 01/2017
1	Retinoblastoma (Glioblastoma, Retinal) 06/2014
1	Osteophyte 02/2014
1	Hypersensitivity (Allergy) 12/2013
1	Brachydactyly 12/2013
1	Hypoglycemia (Reactive Hypoglycemia) 05/2013
1	Acquired Immunodeficiency Syndrome (AIDS) 05/2013
1	Cataract (Cataracts) 05/2013
1	Cardiomegaly (Heart Hypertrophy) 05/2013

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 01/2017 - 04/2004
6	Cetuximab (Erbitux)FDA Link 02/2017 - 05/2013
4	Fluorouracil (Carac)FDA LinkGeneric 02/2017 - 05/2013
4	Transforming Growth Factor alpha (TGF-alpha)IBA 01/2016 - 11/2007
3	Transcription Factors (Transcription Factor)IBA 01/2018 - 06/2008
3	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2018 - 09/2009
3	LigandsIBA 01/2018 - 04/2009
3	Leucovorin (Folinic Acid)FDA Link 02/2017 - 03/2015
3	Irinotecan (Camptosar)FDA LinkGeneric 02/2017 - 03/2015
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2017 - 07/2012
3	Biomarkers (Surrogate Marker)IBA 01/2017 - 01/2007
3	ErbB Receptors (EGF Receptor)IBA 03/2015 - 05/2013
3	Messenger RNA (mRNA)IBA 11/2014 - 11/2007
2	Glycoproteins (Glycoprotein)IBA 01/2022 - 01/2021
2	salicylhydroxamic acid (SHAM)IBA 11/2021 - 12/2018
2	CytokinesIBA 01/2021 - 12/2013
2	ChromatinIBA 01/2017 - 01/2013
2	DNA (Deoxyribonucleic Acid)IBA 03/2015 - 12/2013
2	Metalloproteases (Metalloproteinases)IBA 08/2014 - 04/2013
2	MitogensIBA 02/2014 - 04/2004
2	PPAR gammaIBA 04/2013 - 01/2010
2	Matrix Metalloproteinase 13IBA 04/2013 - 04/2009
2	Aggrecans (Aggrecan)IBA 04/2013 - 04/2009
2	Collagen Type II (Type II Collagen)IBA 04/2013 - 01/2007
2	VaccinesIBA 09/2011 - 11/2010
2	Liposomes (Liposome)IBA 09/2011 - 11/2010
2	Phosphotransferases (Kinase)IBA 05/2011 - 04/2004
2	Calcium PyrophosphateIBA 06/2009 - 01/2008
2	Transforming Growth Factor beta (TGF-beta)IBA 01/2009 - 04/2006
2	p38 Mitogen-Activated Protein KinasesIBA 06/2005 - 04/2004
1	4-O-carboxymethylascochlorinIBA 01/2022
1	Biological ProductsIBA 01/2021
1	PolymersIBA 01/2021
1	SugarsIBA 01/2021
1	Interleukin-6 (Interleukin 6)IBA 07/2020
1	Coe Comfort (FITT)IBA 07/2020
1	Antirheumatic Agents (DMARD)IBA 01/2020
1	Tolonium Chloride FDA Link 12/2018
1	Tartrate-Resistant Acid PhosphataseIBA 12/2018
1	C.I. direct red 80IBA 12/2018
1	Thyroxine (Levothyroxine)FDA LinkGeneric 06/2018
1	Insulin-Like PeptidesIBA 06/2018
1	Hormones (Hormone)IBA 06/2018
1	Insulin-Like Growth Factor I (IGF-1)IBA 06/2018
1	Pharmaceutical PreparationsIBA 01/2018
1	Bevacizumab (Avastin)FDA Link 02/2017
1	Nerve Growth Factor (NGF)IBA 01/2017
1	PeriostinIBA 10/2015
1	Transforming Growth Factors (Transforming Growth Factor)IBA 10/2015
1	Extracellular Matrix ProteinsIBA 10/2015
1	Codon (Codons)IBA 03/2015
1	EmulsionsIBA 03/2015
1	Dual Specificity Phosphatase 1IBA 01/2015
1	Interleukin-10 (Interleukin 10)IBA 12/2013
1	telomestatinIBA 05/2013
1	MineralsIBA 05/2013
1	PlatinumIBA 05/2013
1	Cisplatin (Platino)FDA LinkGeneric 05/2013
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 04/2013

Therapy/Procedure

7	Therapeutics 02/2017 - 01/2010
4	Drug Therapy (Chemotherapy) 01/2017 - 04/2004
2	Bone Plates (Bone Plate) 01/2022 - 01/2021
2	Radiotherapy 05/2013 - 04/2004